Staple‐Based Paper Electrochemical Platform for Celiac Disease Diagnosis

Electrochemical immunosensor for the diagnosis of celiac disease.

A novel electrochemical immunosensing strategy for the detection of antibodies to tissue transglutaminase (tTG) in human serum is presented. The proposed immunosensor consists of the immobilization by physical adsorption of tTG from guinea pig liver on graphite-epoxy composite (GEC) electrodes. After the reaction with the human serum (containing the specific antibodies in the case of celiac dis...

Electrochemical Immunosensors for Celiac Disease Detection

Unfortunately, a high percentage of people with celiac disease (CD) is not yet diagnosed. The disease could begin at any age and the different produced symptoms may complicate the diagnosis, delay the treatment and worsening the living conditions of the patient. Therefore, early diagnosis of the disease when patients have few or not symptoms is really important and can help to improve the patie...

CLINICAL MANIFESTATIONS AND DIAGNOSIS OF CELIAC DISEASE IN CHILDREN

Celiac disease (CD) is defined as a permanent intolerance to gluten with clinical manifestations and abnormal small intestinal mucosa. A case series study was performed to obtain information about clinical manifestations, age of presentation and diagnosis of CD. For this purpose, hospital records of patients who were admitted to the gastrointestinal ward in the Children's Medical Center from 1...

An electrochemical deamidated gliadin antibody immunosensor for celiac disease clinical diagnosis.

The first electrochemical immunosensor (EI) for the detection of antibodies against deamidated gliadin peptides (DGP) is described here. A disposable nanohybrid screen-printed carbon electrode modified with DGP was employed as the transducer's sensing surface. Real serum samples were successfully assayed and the results were corroborated with an ELISA kit. The presented EI is a promising analyt...

Celiac disease: how many biopsies for diagnosis?